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Robert Schwabe

Title of talk: "How injury promotes fibrosis and cancer development in the liver"

Summary of talk: 80-90% of liver cancers develop in a fibrotic liver after decades of chronic liver injury. This presentation will describe links between chronic injury, fibrosis and cancer development, focusing on the role of fibrosis in the development of hepatocellular carcinoma and cholangiocarcinoma.

Short biosketch: Dr. Robert Schwabe is an Associate Professor in the Department of Medicine and in the Institute of Human Nutrition at Columbia University. Dr. Schwabe received his MD as well as a doctoral degree in Immunology from Ludwig-Maximilians-University in Munich, Germany. Dr. Schwabe has authored 93 publications, including senior author papers in Nature Medicine, Cancer Cell and the Journal of Clinical Investigation.

Dr. Schwabe's laboratory is dedicated to studying consequences of liver injury including inflammation, fibrosis and cancer, in order to understand how chronic liver disease progresses and to discover molecular targets that can block this process. Dr. Schwabe is a member of the American Society for the Study of Clinical Investigation. Dr. Schwabe holds several NIH grants and is the past recipient of grants from the NIDDK, the American Liver Foundation, a Research Scholar Award from the American Gastroenterological Association and postdoctoral fellowships from the American Liver Foundation and the German Academic Exchange Service. Dr. Schwabe has served as Associate Editor for Gastroenterology and the Journal of Hepatology and is a member of the Hepatobiliary Pathophysiology study section of the NIH.