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PISA 2017 Preliminary Program

Monday September 25

7:45 AM

7:55 AM

Welcome
Satdarshan Paul S. Monga, University of Pittsburgh and Mark E. Sobel, ASIP

 

Tissue Microenvironment and Organ Pathobiology

Session 1
Barbarians at the Gate: Building a Different Kind of Wall  (Microbiome, Junctions, Injury and Infections)
Chairs: Richard Mitchell, Brigham & Women's Hospital and Kari Nejak-Bowen, University of Pittsburgh

7:55 AM

8:00 AM

Introduction
Kari Nejak-Bowen, University of Pittsburgh

8:00 AM

8:30 AM

Plasticity of the Mucosal Barrier: Insights into Regulation of Epithelial Repair
Asma Nusrat, University of Michigan

8:30 AM

9:00 AM

Oral Microbiome and Pulmonary Hypertension
Alison Morris, University of Pittsburgh

9:00 AM

9:30 AM

Pulmonary Microbiome and Lung Diseases
Barbara Methe,
 University of Pittsburgh

9:30 AM

9:45 AM

Maternal Antibodies, the Neonatal Microbiota and Necrotizing Enterocolitis
Timothy Hand, University of Pittsburgh

9:45 AM

10:00 AM

Abstract-Driven Talk

10:00 AM

10:25 AM

Coffee Break

Session 2
Wound Healing and Inflammation
Chairs: Richard Mitchell, Brigham & Women's Hospital and Cecelia Yates, University of Pittsburgh

10:25 AM

10:30 AM

Introduction
Richard Mitchell, Brigham & Women's Hospital

10:30 AM

11:00 AM

Tissue Engineering Therapies Microvascular Remodeling, Inflammation Resolution and Host
Edward Botchwey, Georgia Institute of Technology

11:00 AM

11:30 AM

How Injury Promotes Fibrosis and Cancer Development in the Liver
Robert Schwabe, Columbia University

11:30 AM

12:00 PM

Auto-Immune Lung Fibrosis and Skin
Carol Bostwick, University of South Carolina

12:00 PM

12:15 PM

More than Skin Deep: Understanding the Variables in Cutaneous Wound Healing
Cecelia Yates, University of Pittsburgh

12:15 PM

12:30 PM

Abstract-Driven Talk

12:30 PM

1:25 PM

Lunch (included)

Session 3
Cancer-associated Stroma and Tumor Immunology: Dismantling the Environmental Protection
Chairs: Satdarshan Paul S. Monga, University of Pittsburgh and Cecelia Yates, University of Pittsburgh

1:25 PM

1:30 PM

Introduction
Cecelia Yates, University of Pittsburgh

1:30 PM

2:00 PM

Regulatory T Cells
Dario Vignali, University of Pittsburgh

2:00 PM

2:30 PM

Tumor Microenvironment
Harold Dvorak, Beth Israel Deaconess Medical Center, Harvard Medical School

2:30 PM

3:00 PM

Next Target for Immune Checkpoint Blockade in Cancer
Hassane Zarour, University of Pittsburgh

3:00 PM

3:15 PM

Abstract-Driven Talk

3:15 PM

3:30 PM

Abstract-Driven Talk

 

Posters

3:30 PM

5:00 PM

View the Posters

ASIP Awards Presentation and Business Meeting

5:15 PM

 

 

9:00 PM

Gateway Clipper Dinner and Cruise (included)

Tuesday, September 26

Session 4
Premetastatic Niche and Regulation of Tumor Metastasis: Instituting a Travel Ban
Chairs: Piyali Dasgupta, Marshall University and Satdarshan Paul S. Monga, University of Pittsburgh

7:55 AM

8:00 AM

Introduction
Piyali Dasgupta, Marshall University

8:00 AM

8:30 AM

Exosomes and Microenvironment
Rama Khoka, University of Toronto

8:30 AM

9:00 AM

Exosomes in Tumor Progression and Treatment
Theresa Whiteside, University of Pittsburgh

9:00 AM

9:30 AM

Tumorigenesis, Metastasis, Wound Healing, Vascular Modeling - Liver (Organs) on Chip
Alan Wells, University of Pittsburgh

9:30 AM

9:45 AM

Abstract-Driven Talk

9:45 AM

10:00 AM

Abstract-Driven Talk

10:00 AM

10:25 AM

Coffee Break

 

Combating Diseases Through Improved Diagnostics and Therapeutics

Session 5
Cancer Epigenetics: Chromatin Landscape to Therapeutics
Chairs: Philip Iannaccone, Northwestern University and William B. Coleman, University of North Carolina at Chapel Hill

10:25 AM

10:30 AM

Introduction
Philip Iannaccone, Northwestern University

10:30 AM

11:00 AM

Histone Modifications in Cancer and Therapeutic Targeting of Histone Modifying Enzymes
Qin Yan, Yale University

11:00 AM

11:30 AM

The Cancer Methylome - Driver of Cancer Development and Target for Cancer Therapy
James Herman, University of Pittsburgh

11:30 AM

12:00 PM

Targeting the Epigenome in Cancer Therapeutics
Sara Sukumar, Johns Hopkins Univrersity

12:00 PM

12:15 PM

Decode mRNA alternative polyadenylation and discover new biology with cTag-PAPERCLIP
Hun-Way Hwang, University of Pittsburgh

12:15 PM

12:30 PM

Abstract-Driven Talk

12:30 PM

1:25 PM

Lunch (included)

Session 6
The Role of Biopsy in Precision Medicine: Making Diagnostics Great Again!
ChairsGregory Tsongalis, Dartmouth-Hitchcock Medical Center and William B. Coleman, University of North Carolina at Chapel Hill

1:25 PM

1:30 PM

Introduction
Gregory Tsongalis, Dartmouth-Hitchcock Medical Center

1:30 PM

2:00 PM

Adequacy of Cytology Specimens: FNA's and Smears for Interrrogation of Genomic Variants
Helen Fernandes, Columbia University Medical Center

2:00 PM

2:30 PM

The ASO TAPUR Trial - A Molecular Driven Approach to Targeted Therapy
Richard L. Schilsky, University of Chicago

2:30 PM

3:00 PM

Cancer Genomics in the Era of NGS
Gregory Tsongalis, Dartmouth-Hitchcock Medical Center

3:00 PM

3:15 PM

Pancreatic Cancer
Aatur Singhi, University of Pittsburgh 

3:15 PM

3:30 PM

Abstract-Driven Talk

Posters and Wine & Cheese Reception

3:30 PM

5:30 PM

View the Posters

 

Wednesday September 27

Session 7
Diagnostic Imaging Modalities: Incredible and Hugely Amazing
ChairsStanley Cohen, Rutgers-NJMS and Cecelia Yates, University of Pittsburgh

7:55 AM

8:10 AM

Introduction
Stanley Cohen, Rutgers - NJMS

8:10 AM

8:40 AM

The Silicon Assistant: Artificial Intelligence and Image Interpretation
Thomas Fuchs, Memorial Sloan Kettering Cancer Center

8:40 AM

9:10 AM

Biomedical Engineering and Imaging Science
Junjie Yao, Duke University

9:10 AM

9:40 AM

Translational Research in the Digital Dome
Yukako Yagi, Memorial Sloan Kettering Cancer Center

9:40 AM

9:55 AM

In vivo and ex vivo imaging reveals a role for Platelet Inflammasome in Sickle Cell Disease

Prithu Sundd, University of Pittsburgh

9:55 AM

10:25 AM

Coffee Break

 

Session 8
Signaling and Therapeutics: Targeting the Bad Hombres
ChairsWilliam B. Coleman, University of North Carolina at Chapel Hill and Satdarshan Paul S. Monga, University of Pittsburgh

10:25 AM

10:30 AM

Introduction
William B. Coleman, Universtiy of North Carolina at Chapel Hill

10:30 AM

11:00 AM

New Approaches to Therapy in Triple-Negative Breast Cancer
Brian Lehmann, Vanderbilt University

11:00 AM

11:30 AM

Targeting beta-catenin for Cancer
Marc Abrams, Dicerna Pharmaceuticals

11:30 AM

12:00 PM

Lung Cancer Epigenetics and Therapeutics
Malabika Sen, University of Pittsburgh

12:00 PM

12:15 PM

Beta-catenin Modulation in Cholestatic Liver Disease
Kari Nejak-Bowen, University of Pittsburgh

12:15 PM

12:30 PM

Abstract-Driven Talk

12:30 PM

Boxed Lunch and Farewell (included)